![]() ![]() The aim of this research was to assess the anticancer activity of these NPs against AGS gastric cancer cells. The resulting refractive index of one PVP-Ag lens was relatively high at 532 nm = 1.545, leading the lens to guide light rays into a small spot of 3.983 µm root mean square and a highest image contrast (lowest MTF curve degradation) of 0.863 ± 0.027 at 20 cycles/mm.Īrtemisia turcomanica extract was utilized to green synthesize Ag, ZnO, and Ag-doped ZnO nanoparticles (NPs). The simulation included the design and simulation of an aberrated human eye based on the Liou and Brennan model and the insertion of the contact lenses for vision correction using the ZEMAX optical design program. This work demonstrates the evaluation of vision correction through each lens and the effect of changing the concentration of Ag NPs on its refractive index. ![]() In this work, three contact lenses were prepared by doping PVP hydrogel with 0.1%, 0.5%, and 1% by weight of laboratory-manufactured silver nanoparticles (Ag NPs). ![]() However, the commercial PVP lenses available today are optically poor, and wearers of PVP medical contact lenses typically experience spherical, coma, astigmatism, and chromatic aberrations due to light dispersion when the pupil is opened at 2.50 mm. This review will comprehensively exemplify representative results of combined therapies of CDT with other antitumor therapies such as chemotherapy, phototherapy, sonodynamic therapy, radiation therapy, magnetic hyperthermia therapy, immunotherapy, starvation therapy, gas therapy, gene therapy, oncosis therapy, or a combination thereof for improving antitumor efficiency from hundreds of the latest literature, introduce strategies such as the ingenious design of nanomedicines and tumor microenvironment regulations to enhance the combination therapy, and further summarize the challenges and future perspective of CDT-based multimodal anticancer therapy.īiocompatible polymers such as poly(vinyl pyrrolidone) (PVP) are used to prepare hydrogels for biomedical applications, optical applications, cosmetic and smart medical contact lenses, and many other applications. With the increasing application of nanotechnology in the medical field, combined therapies based on different types of functional nanomaterials have opened up new avenues for the development of next-generation CDT-enhanced system. However, the catalytic efficiency of reagents involved in the Fenton reaction is severely affected by the inherent microenvironmental limitations of tumors and the strict Fenton reaction-dependent conditions. It is highly selective and safe, without depth limitation of tissue penetration, and shows its potential as a new green therapeutic method with great clinical application. This review illustrates the progress and main principles of nanoscience and nanotechnology and represents the pre-modern as well as modern timeline era of discoveries and milestones in these fields.Ĭhemodynamic therapy (CDT) is well-known for using the tumor microenvironment to activate the Fenton reaction or Fenton-like reaction to generate strong oxidative hydroxyl radicals for tumor-specific treatment. To understand the nature of nanotechnology, it is helpful to review the timeline of discoveries that brought us to the current understanding of this science. Notably, in recent years nanotechnologies have been applied to human health with promising results, especially in the field of cancer treatment. Nanotechnologies contribute to almost every field of science, including physics, materials science, chemistry, biology, computer science, and engineering. The field was subject to a growing public awareness and controversy in the early 2000s, and in turn, the beginnings of commercial applications of nanotechnology. ![]() Nanoscience and nanotechnology represent an expanding research area, which involves structures, devices, and systems with novel properties and functions due to the arrangement of their atoms on the 1–100 nm scale. Nanoscience breakthroughs in almost every field of science and nanotechnologies make life easier in this era. ![]()
0 Comments
Leave a Reply. |